Name
Carl Martin Edwards
Email:
Home: Carl@hyperchat.co.uk
Work: plxcme@pln1.nott.ac.uk
Sex: Male
Date of Birth 14.07.65
Height 5' 11" (180 cm)
Weight 13 st (82 kg)
Summary of Work Experience
11 years post graduate laboratory and scientific writing experience
Developed and used toxicity screens for new chemical entities
Use of a wide range of coagulation assays and protein analysis techniques
Experience as a study site co-ordinator of Phase I, II and III drug trials.
Good oral and written communications skills developed as part of an active research team.
Capable of independent work involving analytical problem solving.
Employment History
1994-1997: Post-Doctoral Research Assistant
'Chemically and physiologically inert oxygen-carrying perfluorocarbons'
(BRITE/EURAM Project No. 7318)
Department of Life Science, Nottingham University.
Employed to assess the toxicity/biocompatibility of novel fluorocarbon emulsions for intra-vascular use.
Established human cell based in vitro assays of biocompatibility as an alternative to in vivo animal tests.
Utilised in vivo methods for biocompatibility assessments of fluorocarbon emulsions and surfactants.
1988-1994: Research Assistant
Department of Surgery, Leicester General Hospital.
Studied the effects of surgical trauma on the coagulation and immune function of renal allograft patients.
Required to learn a wide variety of assays of haemostasis, protein separation and identification methods.
Responsible for managing grants, ordering, COSSH assessments and supervision of MD candidates.
Employed as a Study Site Co-ordinator in the latter part of my contract.
Major Achievements.
Submitted PhD thesis, "Thrombelastographic studies of hypercoagulable clinical states".
Presented at internationally recognised scientfic and surgical meetings.
1986-1988: Laboratory Technician
Department of Microbiology, University of Leicester, University Rd, Leicester
Technician to a taxonomic study of the genus Neisseria, including maintaining a 350 organism culture collection.
Prepared enzyme and electrophoretic protein profiles of clinical isolates.
Major Achievements
Development of novel protease substrates to be used as rapid identification tests.
1991-Present: Part-Time Lecturer
Department of Biology, Charles Keene College, Leicester.
Teach courses to part and full-time students including GCSE Biology, BTEC Microbiology and Access to HE
Designed and received IOB approval for my own courses "Microbiology and Food Hygiene".
Education
1980-1983 10 GCSE 'O' levels at Grade C or above including Mathematics and English.
1983 GCE 'A' levels Pure Mathematics and Statistics(B), Biology(B), Chemistry(B)
1986 BSc Hon. Microbiology 2(ii), UCW Aberystwyth.
1995 PhD "Thrombelastographic studies of hypercoagulable clinical states."
Skills:
Haemostatic Screening: Thrombelastography, PT, APTT, TCT. ELISA D-Dimer and Antithrombin-III. Chromogenic Protein C activity, and Antithrombin-III activity, platelet aggregometry.
FACS analysis: Monocyte DR expression, LeucoGate Sub-population analysis, HUVEC adhesion molecule expression.
Cell Culture: HUVEC primary culture, LCL maintenance, in vitro toxicity screening. Plant protoplast isolation and culture of plant cell suspensions.
Biochemical methods: COBAS MIRA Centrifugal Analyser, LKB-Pharmacia PHAST System, HPLC (LKB System and Waters-Millipore System), PAGE, Isoelectric focusing, 'Rocket' immunoelectrophoresis.
Microbiology: Culture Procedures for fastidious anaerobic and micro-aerophilic organisms and human pathogens up to class 3, bacterial identification procedures including standard and rapid methods ( eg API)
Computer packages: SAS (SGI, VAX), MINITAB (VAX, Mac, IBM), Cricket Graph (Mac, IBM),SuperPaint (Mac), Microsoft Office (Mac, IBM),ChemDraw (Mac), Adobe PhotoShop (Mac), Netscape 2.1 (Mac, IBM).
Professional Membership
British Diabetic Association, Medical and Scientific Section.
Society of Experimental Biology.
British Society of Haemostasis and Thrombosis.
Association for Clincal Reasearch in the Pharmaceutical Industry
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